Myocardial Infarction as a Clinical End Point in Research
نویسندگان
چکیده
منابع مشابه
Nonfatal myocardial infarction is, by itself, an inappropriate end point in clinical trials in cardiology.
In a number of double-blinded, clinical trials in cardiology,1-4 the occurrence of a nonfatal myocardial infarction has served as a secondary end point and, in at least one,5 as the primary end point. We believe that this practice may be inappropriate. An assumption underlying the separate analysis of nonfatal infarction is that there may be pathophysiological differences between fatal and nonf...
متن کاملClinical manifestations of right ventricle involvement in inferior myocardial infarction
Abstract Background: Early diagnosis of right ventricle (RV) involvement in inferior myocardial infarction (Inf MI) is very critical. This study was performed to evaluate the clinical findings of Inf MI with or without RV infarction. Methods: From September 2010 to September 2012, 195 patients with definite diagnosis of Inf MI were evaluated in the Department of Cardiology, in Babol, north of...
متن کاملMyocardial Infarction in a Rhesus Monkey
Myocardial necrosis can be result from a number of causes including nutritional deficiencies, chemical and plant toxins, ischemia and metabolic disorder. The outcome of myocardial necrosis varies depending on the extent of the damage (Donald 2001, Jubb 1993, Radostits 1994, Vanvaleet 1986). Myocardial infarction without demonstrable of atherosclerosis were reported in a rhesus macaque (Gonder 1...
متن کاملTenecteplase versus reteplase in acute myocardial infarction: A network meta-analysis of randomized clinical trials
Background: Acute myocardial infarction (AMI) is the leading cause of death throughout the world. One of the standard approaches to treatment of AMI is fibrinolysis. The study was conducted to evaluate the clinical efficacy of tenecteplase versus reteplase through network meta-analysis for AMI. Methods: Randomized trials were comprehensively searched in PubMed, Scopus, Cochrane library, a...
متن کاملMyocardial infarction as a presentation of clinical in-stent restenosis.
BACKGROUND In-stent restenosis is considered to be a gradual and progressive condition and there is scant data on myocardial infarction (MI) as a clinical presentation. METHODS AND RESULTS Of 2,462 consecutive patients who underwent percutaneous coronary intervention between June 2001 and December 2002, clinical in-stent restenosis occurred in 212 (8.6%), who were classified into 3 groups: ST...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation Research
سال: 2019
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.119.315101